Cell adhesion molecules and adhesion abnormalities in prostate cancer

被引：35

作者：

Mason, MD

Davies, G

Jiang, WG

机构：

[1] Cardiff Univ, Dept Clin Oncol, Cardiff CF14 4XN, S Glam, Wales

[2] Cardiff Univ, Dept Surg, Cardiff CF14 4XN, S Glam, Wales

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2002年 / 41卷 / 01期

关键词：

beta-catenin; cadherin; prostate cancer; cell adhesion;

D O I：

10.1016/S1040-8428(01)00171-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Prostate cancer, the leading male cancer in Western countries, has accelerated in its incidence in the past decade. Patients with prostate cancer frequently have a poor prognosis as a result of local or distant spread of cancer. This review summaries some of the recent progress made in understanding the biology of cancer metastasis with a special emphasis on the role of cell adhesion molecules and adhesion abnormalities. The molecular and cellular function of cell adhesion molecules, their role in cancer and cancer progression, the clinical impact of these molecules, and therapeutic considerations are also discussed. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

收藏

页码：11 / 28

页数：18

相关论文

共 167 条

[1] α-Catenin expression has prognostic value in local and locally advanced prostate cancer [J].

Aaltomaa, S ;

Lipponen, P ;

Ala-Opas, M ;

Eskelinen, M ;

Kosma, VM .

BRITISH JOURNAL OF CANCER, 1999, 80 (3-4) :477-482

[2] Prognostic value of CD44 standard, variant isoforms 3 and 6 and α-catenin expression in local prostate cancer treated by radical prostatectomy [J].

Aaltomaa, S ;

Lipponen, P ;

Viitanen, J ;

Kankkunen, JP ;

Ala-Opas, M ;

Kosma, VM .

EUROPEAN UROLOGY, 2000, 38 (05) :555-562

[3] beta-catenin is a target for the ubiquitin-proteasome pathway [J].

Aberle, H ;

Bauer, A ;

Stappert, J ;

Kispert, A ;

Kemler, R .

EMBO JOURNAL, 1997, 16 (13) :3797-3804

[4] THE E-CADHERIN COMPLEX CONTAINS THE SRC SUBSTRATE P120 [J].

AGHIB, DF ;

MCCREA, PD .

EXPERIMENTAL CELL RESEARCH, 1995, 218 (01) :359-369

[5]

Anastasiadis PZ, 2000, J CELL SCI, V113, P1319

[6] TIGHT JUNCTIONS AND THE MOLECULAR-BASIS FOR REGULATION OF PARACELLULAR PERMEABILITY [J].

ANDERSON, JM ;

VANITALLIE, CM .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1995, 269 (04) :G467-G475

[7] Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1 [J].

Aoki, M ;

Hecht, A ;

Kruse, U ;

Kemler, R ;

Vogt, PK .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (01) :139-144

[8] SOLUBLE FORMS OF THE ADHESION MOLECULE E-CADHERIN IN URINE [J].

BANKS, RE ;

PORTER, WH ;

WHELAN, P ;

SMITH, PH ;

SELBY, PJ .

JOURNAL OF CLINICAL PATHOLOGY, 1995, 48 (02) :179-180

[9] CIRCULATING INTERCELLULAR-ADHESION MOLECULE-1 (ICAM-1), E-SELECTIN AND VASCULAR CELL-ADHESION MOLECULE-1 (VCAM-1) IN HUMAN MALIGNANCIES [J].

BANKS, RE ;

GEARING, AJH ;

HEMINGWAY, IK ;

NORFOLK, DR ;

PERREN, TJ ;

SELBY, PJ .

BRITISH JOURNAL OF CANCER, 1993, 68 (01) :122-124

[10] Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity [J].

Bauer, A ;

Chauvet, S ;

Huber, O ;

Usseglio, F ;

Rothbächer, U ;

Aragnol, D ;

Kemler, R ;

Pradel, J .

EMBO JOURNAL, 2000, 19 (22) :6121-6130

← 1 2 3 4 5 6 7 8 9 10 →