A versatile new synthesis of 4-aryl- and heteroaryl[3,4-c]pyrrolocarbazoles by [4+2] cycloaddition followed by palladium catalysed cross coupling

被引：16

作者：

McCort, G ^{[1
]}

Duclos, O ^{[1
]}

Cadilhac, C ^{[1
]}

Guilpain, E ^{[1
]}

机构：

[1] Synthelabo Rech, Cardiovasc Res, Dept Med Chem, F-91385 Chilly Mazarin, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(99)01142-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Bromo- and 4-trifluorosulfonyloxypyrrolo[3,4-c]carbazoles were prepared in five steps via a [4+2] cycloaddition and were used as key intermediates in palladium-catalysed cross coupling reactions allowing the rapid generation of structurally diverse protein kinase C inhibitors. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：6211 / 6215

页数：5

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