Hybridization chain reaction-based branched rolling circle amplification for chemiluminescence detection of DNA methylation

被引：140

作者：

Bi, Sai ^{[1
,2
]}

Zhao, Tingting ^{[2
]}

Luo, Baoyu ^{[2
]}

Zhu, Jun-Jie ^{[1
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China

[2] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Minist Educ, Key Lab Sensor Anal Tumor Marker, Qingdao 266042, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 61期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

METHYLTRANSFERASE ACTIVITY; SIGNAL AMPLIFICATION; SENSITIVE DETECTION; COLORIMETRIC ASSAY; LABEL; DNAZYME; INHIBITION; PROTEINS; PLATFORM; SYSTEM;

D O I：

10.1039/c3cc43353f

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A novel hybridization chain reaction-based branched rolling circle amplification combining the fabrication of multi-HRP-capped MNPs is developed for chemiluminescence detection of DNA methyltransferase activities and inhibitors with high sensitivity in a well-controlled manner.

引用

收藏

页码：6906 / 6908

页数：3

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