Microbiological and immunological strategies for treatment of inflammatory bowel disease

被引：23

作者：

Steidler, L

机构：

[1] Flanders Interuniv Inst Biotechnol, Dept Mol Biol, B-9000 Ghent, Belgium

[2] State Univ Ghent, B-9000 Ghent, Belgium

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 13期

关键词：

inflammatory bowel disease; immunological therapeutics; delivery; probiotics;

D O I：

10.1016/S1286-4579(01)01476-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chronic inflammatory bowel diseases such as Crohn's disease or ulcerative colitis, affect around 1 in every 1 000 individuals in western countries. They probably result from an inappropriate reaction towards the commensal microflora and are currently treated with antiinflammatory drugs or surgery. Novel strategies aim at blocking lymphocyte recruitment and activation, improved targeting of therapeutics and modification of gut microflora. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：1157 / 1166

页数：10

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