Sequence polymorphism at the tetranucleotide repeat of the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2) locus

被引：43

作者：

Rolf, B

Schurenkamp, M

Junge, A

Brinkmann, B

机构：

[1] INST LEGAL MED,D-48149 MUNSTER,GERMANY

[2] INST LEGAL MED,D-53111 BONN,GERMANY

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1997年 / 110卷 / 02期

关键词：

short tandem repeat; ACTBP2; polymorphism; sequence variation;

D O I：

10.1007/s004140050033

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The tetranucleotide repeat polymorphism in the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2) locus has become a widely used short tandem repeat (STR) system in paternity testing and human identification. The discrimination index of this locus has been reported to be as high as 99.65%. To study the overall variability of this locus, 222 alleles were sequenced in our laboratory. Here, we report the sequences of the 102 different alleles observed, In addition to the length polymorphism, up to ten different sequence variants for single fragment lengths have been detected.

引用

页码：69 / 72

页数：4

共 9 条

[1] POPULATION AND FAMILY DATA OF RFLPS USING SELECTED SINGLE-LOCUS AND MULTILOCUS SYSTEMS [J].