Presence of norepinephrine and other biogenic amines in stonefish venom

被引：29

作者：

Garnier, P

Grosclaude, JM

GoudeyPerriere, F

Gervat, V

Gayral, P

Jacquot, C

Perriere, C

机构：

[1] UNIV PARIS SUD, FAC PHARM, PHARMACOL LAB, F-92296 CHATENAY MALABRY, FRANCE

[2] UNIV PARIS 06, LAB CHIM STRUCT ORGAN & BIOL, F-75252 PARIS 05, FRANCE

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 1996年 / 685卷 / 02期

关键词：

norepinephrine; dopamine; tryptophan;

D O I：

10.1016/S0378-4347(96)00203-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Although fish venoms exert a cardiovascular effect, the presence of adrenergic substances was not previously demonstrated. Chromatographic analysis with electrochemical detection showed the presence of substances co-migrating with norepinephrine, dopamine and tryptophan. Serotonin, which was thought to be implicated in the intense pain following fish envenomation, was not detected. Norepinephrine was identified as a component of the stonefish Synanceia verrucosa venom by gas chromatography-mass spectrometry.

引用

收藏

页码：364 / 369

页数：6

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