Spectrally resolved magnetic resonance imaging of a xenon biosensor

被引：68

作者：

Hilty, C ^{[1
]}

Lowery, TJ

Wemmer, DE

Pines, A

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley, CA 94720 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 01期

关键词：

biosensors; cage compounds; imaging agents; magnetic resonance imaging; xenon;

D O I：

10.1002/anie.200502693

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Going hyper: A continuous flow of water saturated with hyperpolarized xenon through a glass tube assembly containing a xenon biosensor attached through its biotin tag to immobilized avidin-agarose beads (see picture) packed in between two frits results in distinct NMR signals that allow detection of the immobilized avidin analyte with high sensitivity. (Figure Presented) © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：70 / 73

页数：4

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