Human dendritic cell subsets

被引：427

作者：

Collin, Matthew ^{[1
]}

McGovern, Naomi ^{[1
]}

Haniffa, Muzlifah ^{[1
]}

机构：

[1] Newcastle Univ, Inst Cellular Med, Human Dendrit Cell Lab, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

来源：

IMMUNOLOGY | 2013年 / 140卷 / 01期

基金：

英国惠康基金;

关键词：

dendritic cells; haematology; therapy/immunotherapy; HUMAN LANGERHANS CELLS; ANTIGEN-PRESENTING CELLS; T-CELLS; LYMPH-NODES; DISTINCT POPULATIONS; CROSS-PRESENTATION; CUTTING EDGE; STEADY-STATE; DC SUBSET; EXPRESSION;

D O I：

10.1111/imm.12117

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Dendritic cells are highly adapted to their role of presenting antigen and directing immune responses. Developmental studies indicate that DCs originate independently from monocytes and tissue macrophages. Emerging evidence also suggests that distinct subsets of DCs have intrinsic differences that lead to functional specialisation in the generation of immunity. Comparative studies are now allowing many of these properties to be more fully understood in the context of human immunology.

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收藏

页码：22 / 30

页数：9

相关论文

共 102 条

[1]

Microglia: Scapegoat, Saboteur, or Something Else? [J].

Aguzzi, Adriano ;

Barres, Ben A. ;

Bennett, Mariko L. .

SCIENCE, 2013, 339 (6116) :156-161

[2]

Differential regulation of naive and memory CD4+ T cells by alternatively activated dendritic cells [J].

Anderson, Amy E. ;

Sayers, Bethan L. ;

Haniffa, Muzlifah A. ;

Swan, David J. ;

Diboll, Julie ;

Wang, Xiao-Nong ;

Isaacs, John D. ;

Hilkens, Catharien M. U. .

JOURNAL OF LEUKOCYTE BIOLOGY, 2008, 84 (01) :124-133

[3]

Comprehensive analysis of MHC-II expression in healthy human skin [J].

Angel, Catherine E. ;

George, Elizabeth ;

Ostrovsky, Lena L. ;

Dunbar, P. Rod .

IMMUNOLOGY AND CELL BIOLOGY, 2007, 85 (05) :363-369

[4]

Cutting edge:: CD1a+ antigen-presenting cells in human dermis respond rapidly to CCR7 Ligands [J].

Angel, Catherine E. ;

George, Elizabeth ;

Brooks, Anna E. S. ;

Ostrovsky, Lena L. ;

Brown, Tim La H. ;

Dunbar, P. Rod .

JOURNAL OF IMMUNOLOGY, 2006, 176 (10) :5730-5734

[5]

Distinctive localization of antigen-presenting cells in human lymph nodes [J].

Angel, Catherine E. ;

Chen, Chun-Jen J. ;

Horlacher, Oliver C. ;

Winkler, Sintia ;

John, Thomas ;

Browning, Judy ;

MacGregor, Duncan ;

Cebon, Jonathan ;

Dunbar, P. Rod .

BLOOD, 2009, 113 (06) :1257-1267

[6]

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells [J].

Bachem, Annabell ;

Guettler, Steffen ;

Hartung, Evelyn ;

Ebstein, Frederic ;

Schaefer, Michael ;

Tannert, Astrid ;

Salama, Abdulgabar ;

Movassaghi, Kamran ;

Opitz, Corinna ;

Mages, Hans W. ;

Henn, Volker ;

Kloetzel, Peter-Michael ;

Gurka, Stephanie ;

Kroczek, Richard A. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (06) :1273-1281

[7]

Defining dendritic cells by conditional and constitutive cell ablation [J].

Bar-On, Liat ;

Jung, Steffen .

IMMUNOLOGICAL REVIEWS, 2010, 234 :76-89

[8]

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency [J].

Bigley, Venetia ;

Haniffa, Muzlifah ;

Doulatov, Sergei ;

Wang, Xiao-Nong ;

Dickinson, Rachel ;

McGovern, Naomi ;

Jardine, Laura ;

Pagan, Sarah ;

Dimmick, Ian ;

Chua, Ignatius ;

Wallis, Jonathan ;

Lordan, Jim ;

Morgan, Cliff ;

Kumararatne, Dinakantha S. ;

Doffinger, Rainer ;

van der Burg, Mirjam ;

van Dongen, Jacques ;

Cant, Andrew ;

Dick, John E. ;

Hambleton, Sophie ;

Collin, Matthew .

JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 208 (02) :227-234

[9]

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement [J].

Caminschi, Irina ;

Proietto, Anna I. ;

Ahmet, Fatma ;

Kitsoulis, Susie ;

Teh, Joo Shin ;

Lo, Jennifer C. Y. ;

Rizzitelli, Alexandra ;

Wu, Li ;

Vremec, David ;

van Dommelen, Serani L. H. ;

Campbell, Ian K. ;

Maraskovsky, Eugene ;

Braley, Hal ;

Davey, Gayle M. ;

Mottram, Patricia ;

De Velde, Nicholas van ;

Jensen, Kent ;

Lew, Andrew M. ;

Wright, Mark D. ;

Heath, William R. ;

Shortman, Ken ;

Lahoud, Mireille H. .

BLOOD, 2008, 112 (08) :3264-3273

[10]

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon [J].

Cella, M ;

Jarrossay, D ;

Facchetti, F ;

Alebardi, O ;

Nakajima, H ;

Lanzavecchia, A ;

Colonna, M .

NATURE MEDICINE, 1999, 5 (08) :919-923

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