Transfer of autoimmune thyroiditis and resolution of palmoplantar pustular psoriasis following allogeneic bone marrow transplantation

被引：56

作者：

Kishimoto, Y ^{[1
]}

Yamamoto, Y ^{[1
]}

Ito, T ^{[1
]}

Matsumoto, N ^{[1
]}

Ichiyoshi, H ^{[1
]}

Katsurada, T ^{[1
]}

Date, M ^{[1
]}

Ohga, S ^{[1
]}

Kitajima, H ^{[1
]}

Ikehara, S ^{[1
]}

Fukuhara, S ^{[1
]}

机构：

[1] KANSAI MED UNIV,DEPT PATHOL 1,MORIGUCHI,OSAKA 570,JAPAN

来源：

BONE MARROW TRANSPLANTATION | 1997年 / 19卷 / 10期

关键词：

autoimmune thyroiditis; palmoplantar pustular psoriasis; bone marrow transplantation; autoimmunity;

D O I：

10.1038/sj.bmt.1700789

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We report an unusual case of a patient who was cured of one autoimmune disease (palmoplantar pustular psoriasis (PPP)) but developed another autoimmune disease (autoimmune thyroiditis) after allogeneic BMT. A 40-year-old man suffering from AML with PPP underwent allogeneic BMT from his HLA-identical sister for the treatment of AML. The patient experienced complete clearance of the cutaneous PPP despite the cessation of immunosuppressive therapy for over 2 years, However, he developed hyperthyroidism with anti-thyroglobulin antibodies 5 months after BMT, although he had showed normal thyroid functions without anti-thyroglobulin antibodies before BMT, The donor had no history of thyroid diseases and showed normal thyroid functions but was positive for anti-thyroglobulin antibodies, Thus, even when the donor is in a subclinical state, autoimmune thyroiditis may be transferred from donors to recipients by BMT.

引用

页码：1041 / 1043

页数：3

共 13 条

[1] ADOPTIVE TRANSFER OF HYPERTHYROIDISM AND AUTOIMMUNE-THYROIDITIS FOLLOWING ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR CHRONIC MYELOID-LEUKEMIA
ALDOURI, MA
RUGGIER, R
EPSTEIN, O
PRENTICE, HG
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 1990, 74 (01) : 118 - 119
[2] RELAPSING PUSTULAR ERUPTIONS OF THE HANDS AND FEET
ASHURST, PJC
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1964, 76 (04) : 169 - 180
[3] ATKINSON K, 1990, BONE MARROW TRANSPL, V5, P69
[4] CLEARANCE OF SEVERE PSORIASIS AFTER ALLOGENIC BONE-MARROW TRANSPLANTATION
EEDY, DJ
BURROWS, D
BRIDGES, JM
JONES, FGC
[J]. BRITISH MEDICAL JOURNAL, 1990, 300 (6729) : 908 - 908
[5] RATIONALE FOR BONE-MARROW TRANSPLANTATION IN THE TREATMENT OF AUTOIMMUNE-DISEASES
IKEHARA, S
GOOD, RA
NAKAMURA, T
SEKITA, K
INOUE, S
OO, MM
MUSO, E
OGAWA, K
HAMASHIMA, Y
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (08) : 2483 - 2487
[6] ORGAN-SPECIFIC AND SYSTEMIC AUTOIMMUNE-DISEASES ORIGINATE FROM DEFECTS IN HEMATOPOIETIC STEM-CELLS
IKEHARA, S
KAWAMURA, M
TAKAO, F
INABA, M
YASUMIZU, R
THAN, S
HISHA, H
SUGIURA, K
KOIDE, Y
YOSHIDA, TO
IDA, T
IMURA, H
GOOD, RA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (21) : 8341 - 8344
[7] TRANSFER OF INSULIN-DEPENDENT DIABETES BETWEEN HLA-IDENTICAL SIBLINGS BY BONE-MARROW TRANSPLANTATION
LAMPETER, EF
HOMBERG, M
QUABECK, K
SCHAEFER, UW
WERNET, P
BERTRAMS, J
GROSSEWILDE, H
GRIES, FA
KOLB, H
[J]. LANCET, 1993, 341 (8855) : 1243 - 1244
[8] LOWENTHAL RM, 1993, J RHEUMATOL, V20, P137
[9] Rajka G, 1979, Acta Derm Venereol Suppl (Stockh), V87, P31
[10] AUTOIMMUNITY AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION - A STUDY OF 53 LONG-TERM-SURVIVING PATIENTS
ROUQUETTEGALLY, AM
BOYELDIEU, D
PROST, AC
GLUCKMAN, E
[J]. TRANSPLANTATION, 1988, 46 (02) : 238 - 240

← 1 2 →