Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core.

被引：29

作者：

Paterson, I

Fessner, K

Finlay, MRV

Jacobs, MF

机构：

[1] University Chemical Laboratory, Cambridge CB2 1EW, Lensfield Road

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 48期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(96)02083-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Model studies towards the bicyclic acetal core 1 of the zaragozic acids, based on the epoxide cyclisation reaction 4 --> 3, are described. Epoxide 14 provides the desired bicyclic acetal skeleton 16, while epoxide 27 leads through 28 to an isomeric acetal 30. Copyright (C) 1996 Elsevier Science Ltd

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页码：8803 / 8806

页数：4

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