Catalyst Chelation Effects in Organocatalyzed Ring-Opening Polymerization of Lactide

被引:63
作者
Coady, Daniel J. [1 ]
Engler, Amanda C. [1 ]
Horn, Hans W. [1 ]
Bajjuri, Krishna M. [1 ]
Fukushima, Kazuki [1 ]
Jones, Gavin O. [1 ]
Nelson, Alshakim [1 ]
Rice, Julia E. [1 ]
Hedrick, James L. [1 ]
机构
[1] IBM Almaden Res Ctr, San Jose, CA 95120 USA
关键词
BASIS-SETS; ENERGIES; DIAMINES;
D O I
10.1021/mz2000048
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
(-)-Sparteine is a proven organocatalyst for the ring-opening polymerization (ROP) of L-lactide, which affords polymers of controlled molecular weight and narrow polydispersity. The recent worldwide shortage of (-)-sparteine has necessitated the identification of simple and cost-effective replacement ROP catalysts. A series of commercially available molecules was first identified through molecular modeling and then subsequently investigated for polymerizing L-lactide. The modeling proved very useful at predicting spatial relationships and nitrogen geometries that greatly aided in the rapid identification of various alkyl amines as alternative organocatalysts.
引用
收藏
页码:19 / 22
页数:4
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