Models of cell cycle control in eukaryotes

被引:17
作者
Tyson, JJ [1 ]
机构
[1] Virginia Polytech Inst & State Univ, Dept Biol, Blacksburg, VA 24061 USA
关键词
cell cycle control; eukaryotic cells; steady states;
D O I
10.1016/S0168-1656(99)00027-9
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The molecular mechanisms of cell cycle control are now known in enough detail to warrant mathematical modeling by kinetic equations. Despite the repetitive nature of the cell division cycle, the most appropriate models emphasize steady-state solutions rather than limit cycle oscillations, because cells progress toward division-by passing a series of checkpoints (steady states). (C) 1999 Elsevier Science B.V. AII rights reserved.
引用
收藏
页码:239 / 244
页数:6
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