Meat-metabolizing bacteria in atherosclerosis

被引：37

作者：

Backhed, Fredrik ^{[1
,2
]}

机构：

[1] Sahlgrenska Ctr Cardiovasc & Metab Res, Wallenberg Lab, Gothenburg, Sweden

[2] Univ Gothenburg, Dept Mol & Clin Med, Gothenburg, Sweden

来源：

NATURE MEDICINE | 2013年 / 19卷 / 05期

关键词：

GUT MICROBIOTA; METAGENOME; MICE;

D O I：

10.1038/nm.3178

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

L-Carnitine is a common food supplement and naturally occurs in red meat. This nutrient is metabolized into trimethyl metabolites by the gut microbiota and is associated with an elevated risk for cardiovascular disease. A recent study provides new insights into this link by exploring how the gut microbiota generates proatherogenic metabolites from L-carnitine and how the microbiota is altered in response to an omnivorous diet (pages 576–585).

引用

页码：533 / 534

页数：2

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