Biological Basis of Exercise-based Treatments: Spinal Cord Injury

被引：12

作者：

Basso, D. Michele ^{[1
]}

Hansen, Christopher N. ^{[2
]}

机构：

[1] Ohio State Univ, Sch Allied Med Profess, Ctr Brain & Spinal Cord Repair, Columbus, OH 43210 USA

[2] Ohio State Univ, Neurosci Grad Studies Program, Ctr Brain & Spinal Cord Repair, Columbus, OH 43210 USA

来源：

PM&R | 2011年 / 3卷 / 06期

关键词：

SENSORIMOTOR CORTEX; FUNCTIONAL RECOVERY; RATS; MECHANISMS; PLASTICITY; LESIONS; TASK;

D O I：

10.1016/j.pmrj.2011.02.019

中图分类号：

R49 [康复医学];

学科分类号：

100232 [康复医学];

摘要：

Despite intensive neurorehabilitation, extensive functional recovery after spinal cord injury is unattainable for most individuals. Optimal recovery will likely depend on activity-based, task-specific training that personalizes the timing of intervention with the severity of injury. Exercise paradigms elicit both beneficial and deleterious biophysical effects after spinal cord injury. Modulating the type, intensity, complexity, and timing of training may minimize risk and induce greater recovery. This review discusses the following: (a) the biological underpinning of training paradigms that promote motor relearning and recovery, and (b) how exercise interacts with cellular cascades after spinal cord injury. Clinical implications are discussed throughout. PM R 2011;3:S73-S77

引用

页码：S73 / S77

页数：5

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