Antidepressant drugs and experimental inflammation

被引：25

作者：

Bianchi, M ^{[1
]}

Panerai, AE ^{[1
]}

机构：

[1] UNIV MILAN,DEPT PHARMACOL,I-20129 MILAN,ITALY

来源：

PHARMACOLOGICAL RESEARCH | 1996年 / 33卷 / 4-5期

关键词：

antidepressants; oedema; hyperalgesia; prostaglandin; substance P;

D O I：

10.1006/phrs.1996.0032

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

There are strong indications from this brief survey that the anti-inflammatory action of antidepressant drugs is involved in their well documented analgesic effect. In particular, the experimental data reported here contribute to explain the reduction of pain observed after the acute administration of antidepressants in clinical conditions. A better understanding of the mechanisms underlined should lead to improved therapies for pain, and to new compounds for the treatment of inflammation. (C) 1996 The Italian Pharmacological Society.

引用

页码：235 / 238

页数：4

共 36 条

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ARRIGONIMARTELL.E, 1967, EUR J PHARMACOL, V2, P229

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