Exon 8 splice site mutations in the gene encoding the E3-ligase CBL are associated with core binding factor acute myeloid leukemias

被引：58

作者：

Abbas, Saman ^{[1
]}

Rotmans, Gabrielle ^{[1
]}

Lowenberg, Bob ^{[1
]}

Valk, Peter J. M. ^{[1
]}

机构：

[1] Erasmus Univ, Med Ctr, Dept Hematol, NL-3015 GE Rotterdam, Netherlands

来源：

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2008年 / 93卷 / 10期

关键词：

acute myeloid leukemia; mutations; CBL;

D O I：

10.3324/haematol.13187

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1595 / 1597

页数：3

共 9 条

[1] C-kit mutations in core binding factor leukemias [J].

Beghini, A ;

Peterlongo, P ;

Ripamonti, CB ;

Larizza, L ;

Cairoli, R ;

Morra, E ;

Mecucci, C .

BLOOD, 2000, 95 (02) :726-727

[2] Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia [J].

Caligiuri, Michael A. ;

Briesewitz, Roger ;

Yu, Jianhua ;

Wang, Lisheng ;

Wei, Min ;

Arnoczky, Kristy J. ;

Marburger, Trent B. ;

Wen, Jing ;

Perrotti, Danilo ;

Bloomfield, Clara D. ;

Whitman, Susan P. .

BLOOD, 2007, 110 (03) :1022-1024

[3] Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias [J].

Care, RS ;

Valk, PJM ;

Goodeve, AC ;

Abu-Duhier, FM ;

Geertsma-Kleinekoort, WMC ;

Wilson, GA ;

Gari, MA ;

Peake, IR ;

Löwenberg, B ;

Reilly, JT .

BRITISH JOURNAL OF HAEMATOLOGY, 2003, 121 (05) :775-777

[4] Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics:: are we ready for a prognostically prioritized molecular classification? [J].

Mrozek, Krzysztof ;

Marcucci, Guido ;

Paschka, Peter ;

Whitman, Susan P. ;

Bloomfield, Clara D. .

BLOOD, 2007, 109 (02) :431-448

[5] Cooperating gene mutations in acute myeloid leukemia: a review of the literature [J].

Renneville, A. ;

Roumier, C. ;

Biggio, V. ;

Nibourel, O. ;

Boissel, N. ;

Fenaux, P. ;

Preudhomme, C. .

LEUKEMIA, 2008, 22 (05) :915-931

[6] Regulating the regulator: negative regulation of Cbl ubiquitin ligases [J].

Ryan, PE ;

Davies, GC ;

Nau, MM ;

Lipkowitz, S .

TRENDS IN BIOCHEMICAL SCIENCES, 2006, 31 (02) :79-88

[7] Flt3-dependent transformation by inactivating c-Cbl mutations in AML [J].

Sargin, Buelent ;

Choudhary, Chunaram ;

Crosetto, Nicola ;

Schmidt, Mirko H. H. ;

Grundler, Rebekka ;

Rensinghoff, Marion ;

Thiessen, Christine ;

Tickenbrock, Lara ;

Schwaeble, Joachim ;

Brandts, Christian ;

August, Benjamin ;

Koschmieder, Steffen ;

Bandi, Srinivasa Rao ;

Duyster, Justus ;

Berdel, Wolfgang E. ;

Mueller-Tidow, Carsten ;

Dikic, Ivan ;

Serve, Hubert .

BLOOD, 2007, 110 (03) :1004-1012

[8]

Valk PJM, 2004, HAEMATOLOGICA, V89, P106

[9] Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl) [J].

Zeng, S ;

Xu, ZH ;

Lipkowitz, S ;

Longley, JB .

BLOOD, 2005, 105 (01) :226-232

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