Fragmentation studies on tetronasin by accurate-mass electrospray tandem mass spectrometry

被引：29

作者：

Fonseca, T ^{[1
]}

Lopes, NP ^{[1
]}

Gates, PJ ^{[1
]}

Staunton, J ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2004年 / 15卷 / 03期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/j.jasms.2003.10.020

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report here the first full fragmentation study of tetronasin 1. Fragmentation was carried out by high-resolution ESI-CID-MSn. The formulae of the fragment ions were determined by accurate mass measurements. It is demonstrated that the fragmentation routes observed derive essentially from a first loss of water via two different mechanisms. One minor route consists of a charge remote neutral loss and the second major route occurs via the formation of a carbocation. The fragments obtained from this carbocation were produced by subsequent complex neutral eliminations and the structures were inferred, in some cases, by carbocation stability. (C) 2004 American Society for Mass Spectrometry.

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收藏

页码：325 / 335

页数：11

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