Association of Polymorphisms in the promoter region of chicken prolactin with egg production

被引：113

作者：

Cui, JX

Du, HL

Liang, Y

Deng, XM

Li, N

Zhang, XQ ^{[1
]}

机构：

[1] S China Agr Univ, Coll Anim Sci, Dept Anim Genet Breeding & Reprod, Guangzhou 510642, Guangdong, Peoples R China

[2] China Agr Univ, State Key Lab Agrobiotechnol, Beijing 100094, Peoples R China

来源：

POULTRY SCIENCE | 2006年 / 85卷 / 01期

基金：

国家高技术研究发展计划(863计划);

关键词：

chicken; prolactin gene; polymorphism; haplotype; egg production;

D O I：

10.1093/ps/85.1.26

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 [畜牧学];

摘要：

Chicken prolactin (PRL) is a physiological candidate gene for egg production. The objective of the current research was to investigate the association of polymorphisms in the chicken PRL promoter region with egg production. Genotyping of 177 individuals from White Leghorn, Yangshan, Taihe Silkies, White Rock, and Nongdahe breeds for 6 single nucleotide polymorphisms (C-2402T, C-2161G, T-2101G, C-2062G, T-2054A, and G-2040A) and 1 24-bp indel (insertion-deletion) at the site of -358 of the chicken PRL gene revealed large breed differences in allelic frequencies for all but the T-210IG and T-2054A polymorphisms. An F-2 population produced from Nongdahe x Taihe Silkies chickens consisted of 374 hens, which were recorded for egg production traits and genotyped for the above 7 polymorphisms. Marker-trait association analysis indicated that the 24-bp indel was associated with egg production (P < 0.01) and that H3 (C C T C T G) was the most advantageous haplotype for egg production.

引用

页码：26 / 31

页数：6

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