Molecular mechanisms of CNS synaptogenesis

被引：134

作者：

Garner, CC ^{[1
]}

Zhai, RG

Gundelfinger, ED

Ziv, NE

机构：

[1] Stanford Univ, Dept Psychiat & Behav Sci, Palo Alto, CA 94304 USA

[2] Leibniz Inst Neurobiol, Dept Neurochem & Mol Biol, Magdeburg, Germany

[3] Technion Israel Inst Technol, Bruce Rappaport Fac Med, Rappaport Inst, IL-31096 Haifa, Israel

[4] Technion Israel Inst Technol, Bruce Rappaport Fac Med, Dept Anat & Cell Biol, IL-31096 Haifa, Israel

来源：

TRENDS IN NEUROSCIENCES | 2002年 / 25卷 / 05期

关键词：

D O I：

10.1016/S0166-2236(02)02152-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Synapses of the mammalian CNS are asymmetric sites of cell-cell adhesion between nerve cells. They are designed to mediate the rapid and efficient transmission of signals from the presynaptic bouton of one neuron to the postsynaptic plasma membrane of a second neuron. Significant progress has been made in the characterization of the structural, functional and developmental assembly of CNS synapses. Recent progress has been made in understanding the molecular and cellular mechanisms that underlie synaptogenesis, in particular that of glutamatergic synapses of the CNS.

引用

页码：243 / 250

页数：8

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