Reporter Mouse Lines for Fluorescence Imaging

被引:85
作者
Abe, Takaya [1 ]
Fujimori, Toshihiko [1 ,2 ]
机构
[1] RIKEN Ctr Dev Biol CDB, Lab Anim Resources & Genet Engn, Chuo Ku, Kobe, Hyogo 6500047, Japan
[2] Natl Inst Basic Biol, Div Embryol, Okazaki, Aichi 4448787, Japan
关键词
fluorescent protein; live imaging; reporter mouse; ROSA26; EMBRYONIC-STEM-CELLS; SITE-SPECIFIC RECOMBINATION; CRE-MEDIATED RECOMBINATION; TRANSGENIC MICE; IN-VIVO; MONOMERIC RED; UBIQUITOUS EXPRESSION; ES CELLS; WIDESPREAD EXPRESSION; CYTOSKELETON DYNAMICS;
D O I
10.1111/dgd.12062
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The use of live imaging approaches to examine and understand the dynamic processes that take place during mouse development has become widespread. Several groups have reported their success in generating different reporter mouse lines that express a variety of fluorescent markers for imaging. However, there is currently no established database of the reporter mouse lines available for live imaging, such as the Cre transgenic lines (Cre-X-Mice). Researchers therefore often have difficulties in determining which reporter mouse line meets their research purposes. In this review, we summarize some of the reporter mouse lines that have been generated for live imaging studies, and discuss their characteristics.
引用
收藏
页码:390 / 405
页数:16
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