Ecological and evolutionary forces shaping microbial diversity in the human intestine

被引:2589
作者
Ley, RE [1 ]
Peterson, DA [1 ]
Gordon, JI [1 ]
机构
[1] Washington Univ, Sch Med, Ctr Gen Sci, St Louis, MO 63108 USA
关键词
D O I
10.1016/j.cell.2006.02.017
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The human gut is populated with as many as 100 trillion cells, whose collective genome, the microbiome, is a reflection of evolutionary selection pressures acting at the level of the host and at the level of the microbial cell. The ecological rules that govern the shape of microbial diversity in the gut apply to mutualists and pathogens alike.
引用
收藏
页码:837 / 848
页数:12
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