O-succinimidyl-1,3-dimethyl-1,3-trimethyleneuronium salts as efficient reagents in active ester synthesis

被引：11

作者：

Bailén, MA ^{[1
]}

Chinchilla, R ^{[1
]}

Dodsworth, DJ ^{[1
]}

Nájera, C ^{[1
]}

机构：

[1] Univ Alicante, Dept Quim Organ, E-03080 Alicante, Spain

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 09期

关键词：

active esters; N-hydroxysuccinimide; uronium salts; amino acids; areas;

D O I：

10.1016/S0040-4039(02)00090-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The new uronium salts O-succinimidyl-1,3-dimethyl-1,3-trimethyleneuronium hexaftuorophosphate (HSDU) and tetrafluoroborate (TSDU) have been prepared from 1,3-dimethylpropyleneurea (DMPU) and employed in the synthesis of N-hydroxy-succinimide-derived active esters. High yields were obtained at room temperature in short reaction times and no racemization was observed. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1661 / 1664

页数：4

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