Deracemization of 2-alkylcyclohexanones utilizing host-guest molecular association with optically active host compounds in basic suspension media

被引：32

作者：

Tsunoda, T

Kaku, H

Nagaku, M

Okuyama, E

机构：

[1] Faculty of Pharmaceutical Sciences, Tokushima Bunri University

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(97)10071-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Based on host-guest inclusion complexation in the solid state, alpha-substituted cyclohexanones 2a-c were deracemized using optically active host compounds in alkaline conditions to optically active 2 in excellent chemical yield with high enantiomeric excess. (C) 1997 Elsevier Science Ltd.

引用

页码：7759 / 7760

页数：2