Labelling of aminomethylenephosphonate derivatives with generator-produced 188Re, and a study of their stability

被引：12

作者：

Hashimoto, K ^{[1
]}

机构：

[1] Japan Atom Energy Res Inst, Dept Radioisotopes, Tokai, Ibaraki 3191195, Japan

来源：

APPLIED RADIATION AND ISOTOPES | 1999年 / 51卷 / 03期

关键词：

D O I：

10.1016/S0969-8043(99)00047-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The labelling of aminomethylenephosphonate (amp) derivatives (EDTMP; ethylenediamine-N,N,N',N'-tetrakis(methylenephosphonic acid), EDBMP; ethylenediamine-N,N'-bis(methylenephosphonic acid) and NTMP; nitrilotris(methylenephosphonic acid)) with carrier-free Re-188 from the W-188/Re-188 generator was investigated in detail. The stability of the Re-188-amp complex against pH change and dilution with 0.9% NaCl was also studied. It was found that the stability of Re-188-amp was influenced by its formation conditions such as the temperature, pH value and the addition of a carrier. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：307 / 313

页数：7

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