Synthesis of Re-188-MDP complex using carrier-free Re-188

被引:23
作者
Hashimoto, K [1 ]
Bagiawati, S [1 ]
Izumo, M [1 ]
Kobayashi, K [1 ]
机构
[1] NATL ATOM ENERGY AGCY,RADIOISOTOPE PROD CTR,TANGERANG 15310,INDONESIA
关键词
D O I
10.1016/0969-8043(95)00281-2
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The synthesis of a rhenium-MDP labelled compound using carrier-free Re-188 from the W-188/Re-188 generator was investigated. Stannous chloride was used as the reducing agent for the reduction of rhenium. Dependence of the yield of Re-MDP upon the concentration of reducing agent, reaction time, antioxidant, pH, temperature, ionic strength and adding the carrier was examined. Under optimum conditions, the yields of Re-MDP were 85-89% using carrier-free Re-188 and 92-95% using carrier-added Re-188. Furthermore, the stability of Re-MDP at different pHs was studied.
引用
收藏
页码:195 / 199
页数:5
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