Interaction of FtsZ protein with a DPPE Langmuir film

被引:13
作者
Alexandre, S
Colé, G
Coutard, S
Monnier, C
Norris, V
Margolin, W
Yu, X
Valleton, JM
机构
[1] Univ Rouen, UMR 6522 Polymeres Biopolymeres Membranes, CNRS, F-76821 Mont St Aignan, France
[2] Univ Rouen, CNRS, UMR 6037, F-76821 Mont St Aignan, France
[3] Univ Texas, Sch Med, Dept Microbiol, Houston, TX 77030 USA
关键词
DPPE; FtsZ; Langmuir; transfer; atomic force microscopy;
D O I
10.1016/S0927-7765(01)00262-4
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
FtsZ is the key protein in cell division in bacteria. We have proposed that lipid domains in the cytoplasmic membrane play a role in the localisation of FtsZ. In order to test this hypothesis, we used a model system based on Langmuir films to simulate the bacterial membrane. In this simple system we used a single phospholipid, dipalmy-toylphosphatidylethanolamine, which is the major constituent of the inner membrane in Escherichia coli. The first results show clearly the importance of the GTP-controlled assembly process in the appearance of circular or fibrillar structures. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:391 / 395
页数:5
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