Heart failure in older people: causes, diagnosis and treatment

被引:33
作者
Abdelhafiz, AH [1 ]
机构
[1] No Gen Hosp, Sheffield S5 7AU, S Yorkshire, England
关键词
congestive heart failure; diastolic cardiac dysfunction; systolic cardiac dysfunction;
D O I
10.1093/ageing/31.1.29
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Congestive heart failure affects >5% of those aged 65-75 and 10-20% of those aged > 80 in the UK, and levels are likely to rise in the wake of improved therapies for hypertension and myocardial infarction. It is often multi factorial in this group. The most common causes are hypertension and coronary heart disease, with valvular heart disease playing an increasing role. The most common precipitant of pre-existing heart failure is non-compliance with medication or diet; non-steroidal anti-inflammatory drugs arc particularly likely to exacerbate the condition. Diagnosis may be difficult since typical signs arc often absent or masked in older people, but plasma levels of brain natriuretic peptide appear to be a reliable indicator and may provide diagnostic test in the future. Systolic heart failure is managed by conventional therapy (diuretics, angiotensin-converting enzyme inhibitors and beta-blockers). The management of diastolic heart failure is less well defined, but symptoms should be managed, ischaemia prevented and the underlying causes identified and treated. Nurse-directed, multidisciplinary intervention (including education of patient and family, social support, review of medication, dietary modification and weight monitoring) have resulted in improvements in event-free survival and quality of life.
引用
收藏
页码:29 / 36
页数:8
相关论文
共 76 条
[11]  
Cohn J N, 1997, J Card Fail, V3, P173, DOI 10.1016/S1071-9164(97)90013-0
[12]   Rationale and design of the Valsartan Heart Failure Trial: A large multinational trial to assess the effects of valsartan, an angiotensin-receptor blocker, on morbidity and mortality in chronic congestive heart failure [J].
Cohn, JN ;
Tognoni, G ;
Glazer, RD ;
Spormann, D ;
Hester, A .
JOURNAL OF CARDIAC FAILURE, 1999, 5 (02) :155-160
[13]   LOSARTAN IN HEART-FAILURE - HEMODYNAMIC-EFFECTS AND TOLERABILITY [J].
CROZIER, I ;
IKRAM, H ;
AWAN, N ;
CLELAND, J ;
STEPHEN, N ;
DICKSTEIN, K ;
FREY, M ;
YOUNG, J ;
KLINGER, G ;
MAKRIS, L ;
RUCINSKA, E .
CIRCULATION, 1995, 91 (03) :691-697
[14]   Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: comparison with enalapril [J].
Cuocolo, A ;
Storto, G ;
Izzo, R ;
Iovino, GL ;
Damiano, M ;
Bertocchi, F ;
Mann, J ;
Trimarco, B .
JOURNAL OF HYPERTENSION, 1999, 17 (12) :1759-1766
[15]   Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial [J].
Dargie, HJ ;
Colucci, Y ;
Ford, I ;
Sendon, JLL ;
Remme, W ;
Sharpe, N ;
Blank, A ;
Holcslaw, TL .
LANCET, 2001, 357 (9266) :1385-1390
[16]  
DICKSTEIN K, 1994, J HYPERTENS, V12, pS31
[17]   CONGESTIVE HEART-FAILURE WITH NORMAL SYSTOLIC FUNCTION [J].
DOUGHERTY, AH ;
NACCARELLI, GV ;
GRAY, EL ;
HICKS, CH ;
GOLDSTEIN, RA .
AMERICAN JOURNAL OF CARDIOLOGY, 1984, 54 (07) :778-782
[18]   Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease [J].
Doughty, RN ;
Whalley, GA ;
Gamble, G ;
MacMahon, S ;
Sharpe, N ;
Krum, H ;
Murray, Y ;
Tonkin, A ;
Trotter, A ;
Burton, R ;
Garrett, J ;
Lane, G ;
Watts, J ;
Geddes, C ;
Hall, C ;
Stephensen, J ;
Woodhouse, S ;
Davidson, T ;
Bradbury, J ;
Hamer, A ;
Hopkins, L ;
Jackson, D ;
Cross, D ;
Moreland, F ;
Hawtin, B ;
Kimber, V ;
Saunders, M ;
Thomson, A ;
Colquhoun, D ;
Goldsmith, J ;
Hicks, B ;
Bond, C ;
Flett, S ;
Murphy, J ;
Bruning, J ;
Jellyman, T ;
Nairn, L ;
Bartram, H ;
McCulloch, A ;
Milne, A ;
Prasad, R .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 29 (05) :1060-1066
[19]  
Fleischer D, 1997, NEW ZEAL MED J, V110, P71
[20]   Influence of carvedilol on hospitalizations in heart failure: Incidence, resource utilization and costs [J].
Fowler, MB ;
Vera-Llonch, N ;
Oster, G ;
Bristow, MR ;
Cohn, JN ;
Colucci, WS ;
Gilbert, EM ;
Lukas, MA ;
Lacey, MJ ;
Richner, R ;
Young, ST ;
Packer, M .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 37 (06) :1692-1699