Effect of enhanced psychosocial care on antipsychotic use in nurshig home residents with severe dementia: cluster randomised trial

被引:329
作者
Fossey, J
Ballard, C
Juszczak, E
James, I
Aldler, N
Jacoby, R
Howard, R [1 ]
机构
[1] Kings Coll London, Inst Psychiat, MRC, Ctr Neurodegenerat Res, London SE5 8AF, England
[2] Univ Oxford, Oxford OX1 2JD, England
[3] Oxford Mental Healthcare Trust, Oxford, England
[4] Univ Oxford Wolfson Coll, Ctr Stat Med, Oxford OX2 6UD, England
[5] Newcastle Univ, Ctr Hlth Elderly, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
[6] Univ Oxford, Dept Psychiat, Oxford OX1 2JD, England
来源
BMJ-BRITISH MEDICAL JOURNAL | 2006年 / 332卷 / 7544期
关键词
D O I
10.1136/bmj.38782.575868.7C
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To evaluate die effectiveness of a training and support intervention for nursing home staff in reducing the proportion of residents with dementia who are prescribed neuroleptics. Design Cluster randomised controlled trial With blinded assessment of outcome. Setting 12 Specialist nursing homes for people with dementia in London, Newcastle, and Oxford. Participants Residents of the 12 nursing homes; numbers varied during die Study period. Intervention Training and support intervention delivered to nursing home staff over 10 months, focusing Oil alternatives to drugs for the management of agitated behaviour in dementia. Main outcome measures Proportion Of residents in each home who were prescribed neuroleptics and mean levels of agitated and disruptive behaviour (Cohen-Mansfield agitation inventory) in each home at 12 months. Results At 12 months the proportion of residents taking neuroleptics ill I-lie intervention homes (23.0%) was significantly lower than that in the control homes (42.1%): average reduction in neuroleptic use 19.1% (95% confidence interval 0.5% to 37.7%). No significant differences were found in the levels of agitated or disruptive behaviour between intervention and control homes. Conclusions Promotion of person centred care and good practice in the management of patients with dementia with behavioural symptoms provides all effective alternative to neuroleptics.
引用
收藏
页码:756 / 758A
页数:4
相关论文
共 25 条
  • [21] Pharmacological treatment of neuropsychiatric symptoms of dementia - A review of the evidence
    Sink, KM
    Holden, KF
    Yaffe, K
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (05): : 596 - 608
  • [22] Stevens AB, 1998, GERONTOLOGIST, V38, P379
  • [23] Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities -: A double-blind, randomized, placebo-controlled trial
    Street, JS
    Clark, WS
    Gannon, KS
    Cummings, JL
    Bymaster, FP
    Tamura, RN
    Mitan, SJ
    Kadam, DL
    Sanger, TM
    Feldman, PD
    Tollefson, GD
    Breier, A
    [J]. ARCHIVES OF GENERAL PSYCHIATRY, 2000, 57 (10) : 968 - 976
  • [24] Yudkin PL, 2001, STAT MED, V20, P341, DOI 10.1002/1097-0258(20010215)20:3<341::AID-SIM796>3.0.CO
  • [25] 2-G