Immunotherapy Exposes Cancer Stem Cell Resistance and a New Synthetic Lethality

被引：11

作者：

Radvanyi, Laszlo ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Melanoma Med Oncol, Houston, TX 77030 USA

来源：

MOLECULAR THERAPY | 2013年 / 21卷 / 08期

关键词：

DENDRITIC CELLS; CDNA LIBRARIES; ANTIGENS; MELANOMA; TUMORS; CURE;

D O I：

10.1038/mt.2013.160

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1471 / 1473

页数：3

共 16 条

[1] Functional Cloning of Recurrence-specific Antigens Identifies Molecular Targets to Treat Tumor Relapse [J].

Boisgerault, Nicolas ;

Kottke, Timothy ;

Pulido, Jose ;

Thompson, Jill ;

Diaz, Rosa Maria ;

Rommelfanger-Konkol, Diana ;

Embry, Addie ;

Saenz, Dyana ;

Poeschla, Eric ;

Pandha, Hardev ;

Harrington, Kevin ;

Melcher, Alan ;

Selby, Peter ;

Vile, Richard .

MOLECULAR THERAPY, 2013, 21 (08) :1507-1516

[2] INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect [J].

Chiappori, Alberto A. ;

Soliman, Hatem ;

Janssen, William E. ;

Antonia, Scott J. ;

Gabrilovich, Dmitry I. .

EXPERT OPINION ON BIOLOGICAL THERAPY, 2010, 10 (06) :983-991

[3] The secret ally: immunostimulation by anticancer drugs [J].

Galluzzi, Lorenzo ;

Senovilla, Laura ;

Zitvogel, Laurence ;

Kroemer, Guido .

NATURE REVIEWS DRUG DISCOVERY, 2012, 11 (03) :215-233

[4] Cancer immunotherapy with mRNA-transfected dendritic cells [J].

Gilboa, E ;

Vieweg, J .

IMMUNOLOGICAL REVIEWS, 2004, 199 (01) :251-263

[5] EMT: When epithelial cells decide to become mesenchymal-like cells [J].

Kalluri, Raghu .

JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (06) :1417-1419

[6] Immunization with apoptotic pseudovirus transduced cells induces both cellular and humoral responses: A proof of concept study in macaques [J].

Koopman, Gerrit ;

Beenhakker, Niels ;

Hofman, Sam ;

Walther-Jallow, Lilian ;

Makitalo, Barbro ;

Mooij, Petra ;

Anderson, Jan ;

Verschoor, Ernst ;

Bogers, Willy M. J. ;

Heeney, Jonathan L. ;

Spetz, Anna-Lena .

VACCINE, 2012, 30 (15) :2523-2534

[7] Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors [J].

Kottke, Timothy ;

Errington, Fiona ;

Pulido, Jose ;

Galivo, Feorillo ;

Thompson, Jill ;

Wongthida, Phonphimon ;

Diaz, Rosa Maria ;

Chong, Heung ;

Ilett, Elizabeth ;

Chester, John ;

Pandha, Hardev ;

Harrington, Kevin ;

Selby, Peter ;

Melcher, Alan ;

Vile, Richard .

NATURE MEDICINE, 2011, 17 (07) :854-U223

[8] Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes [J].

Liao, XS ;

Li, YQ ;

Bonini, C ;

Nair, S ;

Gilboa, E ;

Greenberg, PD ;

Yee, C .

MOLECULAR THERAPY, 2004, 9 (05) :757-764

[9] Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting [J].

Matsushita, Hirokazu ;

Vesely, Matthew D. ;

Koboldt, Daniel C. ;

Rickert, Charles G. ;

Uppaluri, Ravindra ;

Magrini, Vincent J. ;

Arthur, Cora D. ;

White, J. Michael ;

Chen, Yee-Shiuan ;

Shea, Lauren K. ;

Hundal, Jasreet ;

Wendl, Michael C. ;

Demeter, Ryan ;

Wylie, Todd ;

Allison, James P. ;

Smyth, Mark J. ;

Old, Lloyd J. ;

Mardis, Elaine R. ;

Schreiber, Robert D. .

NATURE, 2012, 482 (7385) :400-U149

[10] Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates [J].

Mire, Chad E. ;

Miller, Andrew D. ;

Carville, Angela ;

Westmoreland, Susan V. ;

Geisbert, Joan B. ;

Mansfield, Keith G. ;

Feldmann, Heinz ;

Hensley, Lisa E. ;

Geisbert, Thomas W. .

PLOS NEGLECTED TROPICAL DISEASES, 2012, 6 (03)

← 1 2 →