Pd/C-catalyzed cyanation of aryl halides in aqueous PEG

被引：95

作者：

Chen, Gong ^{[1
]}

Weng, Jiang ^{[1
]}

Zheng, Zhanchao ^{[1
]}

Zhu, Xinhai ^{[1
]}

Cai, Yaoyao ^{[1
]}

Cai, Jiwen ^{[1
]}

Wan, Yiqian ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 2008卷 / 20期

关键词：

palladium; cyanides; water chemistry; microwaves; sustainable chemistry;

D O I：

10.1002/ejoc.200800295

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An environmentally friendly Pd/C-PEG-H2O system was developed for the cyanation of aryl halides under microwave irradiation. A wide range of aryl bromides, iodides, and some activated chlorides were demonstrated to be cyanated smoothly by using nontoxic K-4[Fe(CN)(6)]center dot 3H(2)O as the cyanide source. There is no phosphorus- or nitrogen-containing ligand or solvent involved. Moreover, this reaction can be carried out without the protection of inert atmosphere. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).

引用

页码：3524 / 3528

页数：5

共 45 条

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