Molecular diagnostics of non-small cell lung cancer using mediastinal lymph nodes sampled by endoscopic ultrasound-guided needle aspiration

被引：10

作者：

Al-Haddad, M ^{[1
]}

Wallace, MB ^{[1
]}

机构：

[1] Mayo Clin Jacksonville, Div Gastroenterol & Hepatol, Jacksonville, FL 32224 USA

来源：

CYTOPATHOLOGY | 2006年 / 17卷 / 01期

关键词：

lung cancer; molecular diagnostics; mediastinal lymphadenopathy; endoscopic ultrasound; fine needle aspiration; EUS FNA; EUS FNAC;

D O I：

10.1111/j.1365-2303.2006.00318.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Non-small cell lung cancer is a common cancer with significant mortality. Accurate and early staging of this cancer has a significant impact on outcome. Endoscopic ultrasound-guided fine needle aspiration of involved mediastinal lymph nodes is critical for staging. Several molecular markers have been identified recently in association with non-small cell carcinoma of the lung that are promising to make early detection of metastatic disease more reliable.

引用

页码：3 / 9

页数：7

共 90 条

[1] Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients [J].

Bostick, PJ ;

Chatterjee, S ;

Chi, DD ;

Huynh, KT ;

Giuliano, AE ;

Cote, R ;

Hoon, DSB .

JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (08) :2632-2640

[2]

Brabender J, 2001, CLIN CANCER RES, V7, P1850

[3] Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer [J].

Cappuzzo, F ;

Hirsch, FR ;

Rossi, E ;

Bartolini, S ;

Ceresoli, GL ;

Bemis, L ;

Haney, J ;

Witta, S ;

Danenberg, K ;

Domenichini, I ;

Ludovini, V ;

Magrini, E ;

Gregorc, V ;

Doglioni, C ;

Sidoni, A ;

Tonato, M ;

Franklin, WA ;

Crino, L ;

Bunn, PA ;

Varella-Garcia, M .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (09) :643-655

[4] Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR [J].

Cassinat, B ;

Zassadowski, F ;

Balitrand, N ;

Barbey, C ;

Rain, JD ;

Fenaux, P ;

Degos, L ;

Vidaud, M ;

Chomienne, C .

LEUKEMIA, 2000, 14 (02) :324-328

[5] FREQUENCY AND DISTRIBUTION OF OCCULT MICROMETASTASES IN LYMPH-NODES OF PATIENTS WITH NON-SMALL-CELL LUNG-CARCINOMA [J].

CHEN, ZL ;

PEREZ, S ;

HOLMES, EC ;

WANG, HJ ;

COULSON, WF ;

WEN, DR ;

COCHRAN, AJ .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1993, 85 (06) :493-498

[6]

COTE RJ, 1995, ANN SURG, V222, P415

[7] Micrometastatic p53-positive cells in the lymph nodes of non-small-cell lung cancer: Prognostic significance [J].

Dobashi, K ;

Sugio, K ;

Osaki, T ;

Oka, T ;

Yasumoto, K .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1997, 114 (03) :339-346

[8]

Dowlatshahi K, 1997, CANCER, V80, P1188, DOI 10.1002/(SICI)1097-0142(19971001)80:7<1188::AID-CNCR2>3.0.CO

[9]

2-H

[10] Metastases from non-small cell lung cancer: Mediastinal staging in the 1990s - Meta-analytic comparison of PET and CT [J].

Dwamena, BA ;

Sonnad, SS ;

Angobaldo, JO ;

Wahl, RL .

RADIOLOGY, 1999, 213 (02) :530-536

← 1 2 3 4 5 6 7 8 9 →