Location, location, location: B-cell differentiation in the gut lamina propria

被引：44

作者：

Cerutti, A. ^{[1
,2
]}

机构：

[1] Cornell Univ, Weill Med Coll, Dept Pathol & Lab Med, New York, NY 10021 USA

[2] Cornell Univ, Weill Grad Sch Med Sci, New York, NY 10021 USA

来源：

MUCOSAL IMMUNOLOGY | 2008年 / 1卷 / 01期

关键词：

D O I：

10.1038/mi.2007.8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The intestinal immune system includes an immunoglobulin (Ig)A-inductive site represented by Peyer's patches (PPs) and an IgA effector site represented by the lamina propria (LP). This canonical map of intestinal IgA production has been blurred recently by studies showing the presence of active IgA class switching in the LP. Here we discuss the functional implications and controversial nature of these findings.

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页码：8 / 10

页数：3

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