Intranuclear inclusions in cells infected with Newcastle Disease Virus

被引：6

作者：

Granzow, H ^{[1
]}

Weiland, F

Mundt, E

Köllner, B

Werner, O

机构：

[1] Fed Res Ctr Virus Dis Anim, Friedrich Loeffler Inst, Inst Diagnost Virol, D-17498 Insel Riems, Germany

[2] Fed Res Ctr Virus Dis Anim, Fiedrich Loeffler Inst, Inst Mol & Cellular Virol, D-17498 Insel Riems, Germany

[3] Fed Res Ctr Virus Dis Anim, Friedrich Loeffler Inst, Inst Appl Virol, D-17498 Insel Riems, Germany

[4] Fed Res Ctr Virus Dis Anim, Inst Microbiol, D-72076 Tubingen, Germany

来源：

JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH | 1999年 / 46卷 / 06期

关键词：

D O I：

10.1046/j.1439-0450.1999.00248.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Cells infected by Newcastle Disease Virus were observed to contain buch intracytoplasmic and intranuclear inclusion bodies. Ultrastructurally, they consisted of twisted strands of about 18-20 nm diameter resembling nucleocapsids. The presence of these inclusions was detected irrespective of host cell or pathogenicity of the virus. In immunofluorescence and immunogold labelling experiments, these structures were tagged by an anti-P protein monoclonal antibody. In summary, we show that intracytoplasmic and intranuclear inclusion bodies, hitherto used as a taxonomic characteristic for the genus Morbillivirus of the Paramyxoviridae, also occur in a member of the genus Rubulavirus.

引用

页码：411 / 421

页数：11

共 41 条

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