Genome of the red alga Porphyridium purpureum

被引：166

作者：

Bhattacharya, Debashish ^{[1
,2
]}

Price, Dana C. ^{[1
,2
]}

Chan, Cheong Xin ^{[3
,4
]}

Qiu, Huan ^{[1
,2
]}

Rose, Nicholas ^{[5
]}

Ball, Steven ^{[6
]}

Weber, Andreas P. M. ^{[7
]}

Arias, Maria Cecilia ^{[6
]}

Henrissat, Bernard ^{[8
]}

Coutinho, Pedro M. ^{[8
]}

Krishnan, Anagha ^{[9
]}

Zaeuner, Simone ^{[10
]}

Morath, Shannon ^{[11
]}

Hilliou, Frederique ^{[12
,13
]}

Egizi, Andrea ^{[14
]}

Perrineau, Marie-Mathilde ^{[1
,2
]}

Yoon, Hwan Su ^{[15
]}

机构：

[1] Rutgers State Univ, Dept Ecol Evolut & Nat Resources, New Brunswick, NJ 08901 USA

[2] Rutgers State Univ, Inst Marine & Coastal Sci, New Brunswick, NJ 08901 USA

[3] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia

[4] Univ Queensland, ARC Ctr Excellence Bioinformat, Brisbane, Qld 4072, Australia

[5] Rutgers State Univ, Dept Biochem & Microbiol, New Brunswick, NJ 08901 USA

[6] Univ Sci & Technol Lille, UMR CNRS USTL 8576, Unite Glycobiol Struct & Fonct, F-59655 Villeneuve Dascq, France

[7] Univ Dusseldorf, Inst Plant Biochem, Ctr Excellence Plant Sci CEPLAS, D-40225 Dusseldorf, Germany

[8] Aix Marseille Univ, CNRS UMR 7257, F-13288 Marseille, France

[9] Rutgers State Univ, Waksman Inst Microbiol, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA

[10] Univ Bonn, Inst Mol Physiol & Biotechnol Plants IMBIO, D-53115 Bonn, Germany

[11] Rutgers State Univ, Dept Plant Biol & Pathol, New Brunswick, NJ 08901 USA

[12] UMR 1355 Inst Sophia Agrobiotech, Inst Natl Rech Agron, F-0690 Sophia Antipolis, France

[13] Univ Nice Sophia Antipolis, UMR 7254, CNRS, F-06903 Sophia Antipolis, France

[14] Rutgers State Univ, Grad Program Ecol & Evolut, Dept Entomol, New Brunswick, NJ 08901 USA

[15] Sungkyunkwan Univ, Dept Biol Sci, Suwon 440746, South Korea

来源：

NATURE COMMUNICATIONS | 2013年 / 4卷

基金：

美国国家科学基金会;

关键词：

CYANIDIOSCHYZON-MEROLAE; GENE-TRANSFER; MEIOTIC GENES; EVOLUTION; SEQUENCE; PHYCOBILISOME; BIOSYNTHESIS; POLYPEPTIDE; PROTEINS; CRUENTUM;

D O I：

10.1038/ncomms2931

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The limited knowledge we have about red algal genomes comes from the highly specialized extremophiles, Cyanidiophyceae. Here, we describe the first genome sequence from a mesophilic, unicellular red alga, Porphyridium purpureum. The 8,355 predicted genes in P. purpureum, hundreds of which are likely to be implicated in a history of horizontal gene transfer, reside in a genome of 19.7 Mbp with 235 spliceosomal introns. Analysis of light-harvesting complex proteins reveals a nuclear-encoded phycobiliprotein in the alga. We uncover a complex set of carbohydrate-active enzymes, identify the genes required for the methylerythritol phosphate pathway of isoprenoid biosynthesis, and find evidence of sexual reproduction. Analysis of the compact, function-rich genome of P. purpureum suggests that ancestral lineages of red algae acted as mediators of horizontal gene transfer between prokaryotes and photosynthetic eukaryotes, thereby significantly enriching genomes across the tree of photosynthetic life.

引用

页数：10

共 60 条

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