The puzzling origin of the genetic code

被引：13

作者：

Cedergren, R

Miramontes, P

机构：

[1] Département de Biochimie, Université de Montréal, Montréal

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 06期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0968-0004(96)80014-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent results add to the mystery of the origin of the genetic code. In spite of early doubts, RNA can discriminate between hydrophobic amino acids under certain contexts. Moreover, codon reassignment, which has taken place in several organisms and mitochondria, is not a random process. Finally, phylogenies of some aminoacyl-tRNA synthetases suggest that the entire code was not completely assigned at the time of the divergence of bacteria from nucleated cells.

引用

页码：199 / 200

页数：2

共 15 条

[1] SEQUENCE AND ORGANIZATION OF THE HUMAN MITOCHONDRIAL GENOME
ANDERSON, S
BANKIER, AT
BARRELL, BG
DEBRUIJN, MHL
COULSON, AR
DROUIN, J
EPERON, IC
NIERLICH, DP
ROE, BA
SANGER, F
SCHREIER, PH
SMITH, AJH
STADEN, R
YOUNG, IG
[J]. NATURE, 1981, 290 (5806) : 457 - 465
[2] [Anonymous], 1967, GENETIC CODE
[3] Baron Christian, 1995, P529
[4] ORIGIN OF GENETIC CODE
CRICK, FHC
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1968, 38 (03) : 367 - &
[5] DEPOUPLANA LR, 1995, P NATL ACAD SCI USA, V93, P166
[6] GAGNON Y, IN PRESS J BIOL CHEM
[7] AMINOACYL-RNA SYNTHESIS CATALYZED BY AN RNA
ILLANGASEKARE, M
SANCHEZ, G
NICKLES, T
YARUS, M
[J]. SCIENCE, 1995, 267 (5198) : 643 - 647
[8] KEELING PJ, IN PRESS EMBO J
[9] LABUDA D, 1981, BIOCHIMIE, V63, P77, DOI 10.1016/S0300-9084(81)80150-2
[10] EVOLUTION OF THE GLX-TRANSFER-RNA SYNTHETASE FAMILY - THE GLUTAMINYL ENZYME AS A CASE OF HORIZONTAL GENE-TRANSFER
LAMOUR, V
QUEVILLON, S
DIRIONG, S
NGUYEN, VC
LIPINSKI, M
MIRANDE, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (18) : 8670 - 8674

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