Electrical monitoring of gel-protected bilayer lipid membranes using a bipotentiostat

被引：3

作者：

Beddow, JA ^{[1
]}

Peterson, IR ^{[1
]}

Heptinstall, J ^{[1
]}

Walton, DJ ^{[1
]}

机构：

[1] Coventry Univ, Ctr Mol & Biomol Elect, NES, Coventry CV1 5FB, W Midlands, England

来源：

INTERNATIONAL CONFERENCE ON SENSOR TECHNOLOGY (ISTC 2001), PROCEEDINGS | 2001年 / 4414卷

关键词：

bilayer; gel-protected; bipotentiostat; four-electrode; biosensor; glycerol; 1-monoleate; valinomycin;

D O I：

10.1117/12.440153

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Electrically monitored lipid bilayer membranes, protected from mechanical damage and contact with low-energy liquids by a hydrogel layer, show promise in biosensing applications. We describe the principle and implementation of a bipotentiostatic circuit for the measurement of both resistance and capacitance of gel-protected membranes. We report measurements taken using the bipotentiostat of membranes formed using glycerol 1-monooleate, and the response of these membranes to the ionophore, valinomycin.

引用

页码：62 / 69

页数：8