Copper(I) Iodide Catalyzed Domino Process to Quinazolin-4(3H)-ones

被引：49

作者：

Zhou, Jing ^{[1
,2
]}

Fu, Liangbing ^{[1
,2
]}

Lv, Man ^{[1
,2
]}

Liu, Jinsong ^{[2
]}

Pei, Duanqing ^{[1
,2
]}

Ding, Ke ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Lab Regenerat Biol, Guangzhou 510663, Guangdong, Peoples R China

[2] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, State Key Lab Resp Dis, Guangzhou 510663, Guangdong, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2008年 / 24期

关键词：

quinazolin-4(3H)-ones; one-pot; ligand-free; copper(I) iodide; coupling/condensative cyclization;

D O I：

10.1055/s-0028-1083245

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of substituted quinazolin-4(3H)-ones by a one-pot ligand-free Cul-catalyzed coupling/condensative cyclization under mild conditions is described. Our study provides an alternative strategy for the preparation of biologically active quinazolin-4(3H)-ones.

引用

页码：3974 / 3980

页数：7

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