Recent advances of protein microarrays

被引:88
作者
Hultschig, C [1 ]
Kreutzberger, J [1 ]
Seitz, H [1 ]
Konthur, Z [1 ]
Büssow, K [1 ]
Lehrach, H [1 ]
机构
[1] Max Planck Inst Mol Genet, Dept Vertebrate Genom, D-14195 Berlin, Germany
关键词
D O I
10.1016/j.cbpa.2005.12.011
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Technological innovations and novel applications have greatly advanced the field of protein microarrays. Over the past two years, different types of protein microarrays have been used for serum profiling, protein abundance determinations, and identification of proteins that bind DNA or small compounds. However, considerable development is still required to ensure common quality standards and to establish large content repertoires. Here, we summarize applications available to date and discuss recent technological achievements and efforts on standardization.
引用
收藏
页码:4 / 10
页数:7
相关论文
共 60 条
[1]   Subnanoliter enzymatic assays on microarrays [J].
Angenendt, P ;
Lehrach, H ;
Kreutzberger, J ;
Glökler, J .
PROTEOMICS, 2005, 5 (02) :420-425
[2]   Next generation of protein microarray support materials:: Evaluation for protein and antibody microarray applications [J].
Angenendt, P ;
Glökler, J ;
Sobek, J ;
Lehrach, H ;
Cahill, DJ .
JOURNAL OF CHROMATOGRAPHY A, 2003, 1009 (1-2) :97-104
[3]   3D protein microarrays:: Performing multiplex immunoassays on a single chip [J].
Angenendt, P ;
Glökler, J ;
Konthur, Z ;
Lehrach, H ;
Cahill, DJ .
ANALYTICAL CHEMISTRY, 2003, 75 (17) :4368-4372
[4]   Toward optimized antibody microarrays:: a comparison of current microarray support materials [J].
Angenendt, P ;
Glökler, J ;
Murphy, D ;
Lehrach, H ;
Cahill, DJ .
ANALYTICAL BIOCHEMISTRY, 2002, 309 (02) :253-260
[5]   Progress in protein and antibody microarray technology [J].
Angenendt, P .
DRUG DISCOVERY TODAY, 2005, 10 (07) :503-511
[6]   Minimum information about a microarray experiment (MIAME) - toward standards for microarray data [J].
Brazma, A ;
Hingamp, P ;
Quackenbush, J ;
Sherlock, G ;
Spellman, P ;
Stoeckert, C ;
Aach, J ;
Ansorge, W ;
Ball, CA ;
Causton, HC ;
Gaasterland, T ;
Glenisson, P ;
Holstege, FCP ;
Kim, IF ;
Markowitz, V ;
Matese, JC ;
Parkinson, H ;
Robinson, A ;
Sarkans, U ;
Schulze-Kremer, S ;
Stewart, J ;
Taylor, R ;
Vilo, J ;
Vingron, M .
NATURE GENETICS, 2001, 29 (04) :365-371
[7]   A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library [J].
Büssow, K ;
Cahill, D ;
Nietfeld, W ;
Bancroft, D ;
Scherzinger, E ;
Lehrach, H ;
Walter, G .
NUCLEIC ACIDS RESEARCH, 1998, 26 (21) :5007-5008
[8]   Enzymatic activity on a chip: The critical role of protein orientation [J].
Cha, T ;
Guo, A ;
Zhu, XY .
PROTEOMICS, 2005, 5 (02) :416-419
[9]   Protein microarrays for multiplex analysis of signal transduction pathways [J].
Chan, SM ;
Ermann, J ;
Su, L ;
Fathman, CG ;
Utz, PJ .
NATURE MEDICINE, 2004, 10 (12) :1390-1396
[10]   Luminescent quantum dots for multiplexed biological detection and imaging [J].
Chan, WCW ;
Maxwell, DJ ;
Gao, XH ;
Bailey, RE ;
Han, MY ;
Nie, SM .
CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (01) :40-46