A Two-Channel Ratiometric Electrochemical Biosensor for InVivo Monitoring of Copper Ions in a Rat Brain Using Gold Truncated Octahedral Microcages

被引：135

作者：

Chai, Xiaolan ^{[1
]}

Zhou, Xinguang ^{[2
]}

Zhu, Anwei ^{[1
]}

Zhang, Limin ^{[1
]}

Qin, Yao

Shi, Guoyue ^{[2
]}

Tian, Yang ^{[1
,3
]}

机构：

[1] Tongji Univ, Dept Chem, Shanghai 200092, Peoples R China

[2] E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China

[3] Tongji Univ, Inst Adv Mat & Nano Biomed, Shanghai 200092, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 31期

关键词：

biosensors; brain; copper ions; electrochemistry; SUPEROXIDE-DISMUTASE; ELECTRON-TRANSFER; ZINC; PRECONCENTRATION; NEUROTOXICITY; ALZHEIMERS; CADMIUM; SAMPLES; CU(II); CELLS;

D O I：

10.1002/anie.201302958

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Brain chemistry: A biosensor has been developed for in vivo determination of copper ions in a rat brain by using gold truncated octahedral microcages. The significant analytical performance of the present biosensor, as well as the properties of a carbon fiber microelectrode have provided a direct and reliable approach for monitoring cerebral metal ions (W.E.=working electrode; see picture). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：8129 / 8133

页数：5

共 40 条

[1]

[Anonymous], 2009, ANGEW CHEM INT ED, V48, P2044

[2]

[Anonymous], 2008, ANGEW CHEM INT ED, V47, P7454

[3]

[Anonymous], 2012, ANGEW CHEM INT ED, V51, P7185

[4]

[Anonymous], 2012, ANGEW CHEM INT ED, V51, P6648

[5] Quantitative imaging of selenium, copper, and zinc in thin sections of biological tissues (Slugs-Genus arion) measured by laser ablation inductively coupled of plasma mass spectrometry [J].

Becker, J. S. ;

Matusch, A. ;

Depboylu, C. ;

Dobrowolska, J. ;

Zoriy, M. V. .

ANALYTICAL CHEMISTRY, 2007, 79 (16) :6074-6080

[6] PREPARATION OF SELECTIVELY METAL-FREE AND METAL-SUBSTITUTED DERIVATIVES BY REACTION OF CU-ZN SUPEROXIDE-DISMUTASE WITH DIETHYLDITHIOCARBAMATE [J].

COCCO, D ;

CALABRESE, L ;

RIGO, A ;

MARMOCCHI, F ;

ROTILIO, G .

BIOCHEMICAL JOURNAL, 1981, 199 (03) :675-680

[7] Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis) [J].

Gaggelli, Elena ;

Kozlowski, Henryk ;

Valensin, Daniela ;

Valensin, Gianni .

CHEMICAL REVIEWS, 2006, 106 (06) :1995-2044

[8]

Ino K., 2012, Angew. Chem., V124, P6752

[9] Anodic stripping voltammetric determination of copper(II) using a functionalized carbon nanotubes paste electrode modified with crosslinked chitosan [J].

Janegitz, Bruno C. ;

Marcolino-Junior, Luiz H. ;

Campana-Filho, Sergio P. ;

Faria, Ronaldo C. ;

Fatibello-Filho, Orlando .

SENSORS AND ACTUATORS B-CHEMICAL, 2009, 142 (01) :260-266

[10] Effect of Dexamethasone on Gliosis, Ischemia, and Dopamine Extraction during Microdialysis Sampling in Brain Tissue [J].

Jaquins-Gerstl, Andrea ;

Shu, Zhan ;

Zhang, Jing ;

Liu, Yansheng ;

Weber, Stephen G. ;

Michael, Adrian C. .

ANALYTICAL CHEMISTRY, 2011, 83 (20) :7662-7667

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