Treatment for the procoagulant state in type 2 diabetes

被引：30

作者：

Colwell, JA

机构：

[1] Med Univ S Carolina, Ctr Diabet, Charleston, SC 29425 USA

[2] Med Univ S Carolina, Dept Med, Charleston, SC 29425 USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2001年 / 30卷 / 04期

关键词：

D O I：

10.1016/S0889-8529(05)70225-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This article discusses the procoagulent state in type 2 diabetes mellitus. There are alterations of the intrinsic coagulation system, fibrinolysis, and platelet function, which contribute to a prothrombotic state in many people with diabetes. Therapeutic approaches are presented, including a rationale for intensive glycemic regulation and aspirin therapy for diabetic individuals who are at high vascular risk.

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收藏

页码：1011 / +

页数：21

相关论文

共 84 条

[61]

SARJI KE, 1976, MICROCIRCULATION, V2, P296

[62]

SCHNEIDER DJ, 1983, LANCET, V1, P786

[63] The role of platelets in diabetes-related vascular complications [J].

Sobol, AB ;

Watala, C .

DIABETES RESEARCH AND CLINICAL PRACTICE, 2000, 50 (01) :1-16

[64] DIABETES, OTHER RISK-FACTORS, AND 12-YR CARDIOVASCULAR MORTALITY FOR MEN SCREENED IN THE MULTIPLE RISK FACTOR INTERVENTION TRIAL [J].

STAMLER, J ;

VACCARO, O ;

NEATON, JD ;

WENTWORTH, D .

DIABETES CARE, 1993, 16 (02) :434-444

[65] INFLUENCE OF DIABETES-MELLITUS ON EARLY AND LATE OUTCOME AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY [J].

STEIN, B ;

WEINTRAUB, WS ;

GEBHART, SSP ;

COHENBERNSTEIN, CL ;

GROSSWALD, R ;

LIBERMAN, HA ;

DOUGLAS, JS ;

MORRIS, DC ;

KING, SB .

CIRCULATION, 1995, 91 (04) :979-989

[66] SECRETION OF PLASMINOGEN-ACTIVATOR INHIBITOR-1 FROM CULTURED HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS IS INDUCED BY VERY LOW-DENSITY-LIPOPROTEIN [J].

STIKORAHM, A ;

WIMAN, B ;

HAMSTEN, A ;

NILSSON, J .

ARTERIOSCLEROSIS, 1990, 10 (06) :1067-1073

[67] STUDIES ON MECHANISMS INVOLVED IN HYPOGLYCEMIA-INDUCED PLATELET ACTIVATION [J].

TROVATI, M ;

ANFOSSI, G ;

CAVALOT, F ;

VITALI, S ;

MASSUCCO, P ;

MULARONI, E ;

SCHINCO, P ;

TAMPONI, G ;

EMANUELLI, G .

DIABETES, 1986, 35 (07) :818-825

[68] INSULIN DIRECTLY REDUCES PLATELET SENSITIVITY TO AGGREGATING AGENTS - STUDIES INVITRO AND INVIVO [J].

TROVATI, M ;

ANFOSSI, G ;

CAVALOT, F ;

MASSUCCO, P ;

MULARONI, E ;

EMANUELLI, G .

DIABETES, 1988, 37 (06) :780-786

[69] EXPOSURE OF ADHESION MOLECULES ON ACTIVATED PLATELETS IN PATIENTS WITH NEWLY-DIAGNOSED IDDM IS NOT NORMALIZED BY NEAR-NORMOGLYCEMIA [J].

TSCHOEPE, D ;

DRIESCH, E ;

SCHWIPPERT, B ;

NIEUWENHUIS, HK ;

GRIES, FA .

DIABETES, 1995, 44 (08) :890-894

[70] PLATELETS IN DIABETES - THE ROLE IN THE HEMOSTATIC REGULATION IN ATHEROSCLEROSIS [J].

TSCHOEPE, D ;

ROESEN, P ;

SCHWIPPERT, B ;

GRIES, FA .

SEMINARS IN THROMBOSIS AND HEMOSTASIS, 1993, 19 (02) :122-128

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