Enantiodivergent synthesis of both enantiomeric forms of substituted paraconic acids starting from D-mannitol as a chiral pool

被引：44

作者：

Masaki, Y ^{[1
]}

Arasaki, H ^{[1
]}

Itoh, A ^{[1
]}

机构：

[1] Gifu Pharmaceut Univ, Gifu 5028585, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(99)00855-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetamide-acetal Claisen rearrangement of the C-2-symmetric enediol easily derived from D-mannitol provided a chiral C8-building block, which was demonstrated to be versatile for divergent synthesis of both enantiomeric forms of substituted paraconic acids. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：4829 / 4832

页数：4

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