Survival in France after childhood acute leukaemia and non-Hodgkin's lymphoma (1990-2000)

被引：23

作者：

Goubin, A ^{[1
]}

Auclerc, MF

Auvrignon, A

Patte, C

Bergeron, C

Hémon, D

Clavel, J

机构：

[1] INSERM, U754, Villejuif, France

[2] Univ Paris Sud, IFR69, Villejuif, France

[3] French Natl Registry Childhood Leukaemia & Lympho, Villejuif, France

[4] Hop St Louis, FRALLE Grp, Paris, France

[5] Hop Trousseau, LAME Grp, Paris, France

[6] LMB, Inst Gustave Roussy, Villejuif, France

[7] LMT, Ctr Leon Berard, Lyon, France

来源：

EUROPEAN JOURNAL OF CANCER | 2006年 / 42卷 / 04期

关键词：

children; survival; acute leukaemia; lymphoma; population-based cancer registry; France;

D O I：

10.1016/j.ejca.2005.08.041

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This article describes the survival after childhood acute leukaemia (AL) and non-Hodgkin's lymphoma (NHL) of French population aged less than 15 years. The French National Registry of Childhood Leukaemia and Lymphoma recorded 3995 cases of acute lymphoblastic leukaemia (ALL), 812 of acute myeloid leukaemia (AML) and 1137 of NHL over the period from 1990 to 2000. Overall survival rates at 5 years were 82% (95% CI 80-83), 58% (95% CI 54-61) and 87% (95% CI 85-89) for ALL, AML and NHL, respectively. Survival after AL increased from 77% (95% Cl 75-80) in 1990-1992 to 85% (95% Cl 83-87) in 1997-2000 for ALL and from 47% (95% CI 41-54) to 61% (95% CI 55-67) for AML. Among AL cases, children aged 1-4 years had the most favourable prognosis. Down's syndrome was associated with poor survival after ALL. No gender-related variations in survival were in evidence. The results reported herein are similar to those reported by other European registries and clinical trials. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：534 / 541

页数：8

共 31 条

[21] Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study [J].