Mutational screen reveals a novel JAK2 mutation, L611S, in a child with acute lymphoblastic leukemia

被引：59

作者：

Kratz, CP

Böll, S

Kontny, U

Schrappe, M

Niemeyer, CM

Stanulla, M

机构：

[1] Univ Freiburg, Div Pediat Hematol & Oncol, Dept Pediat & Adolescent Med, D-7800 Freiburg, Germany

[2] Univ Kiel, Dept Pediat, D-2300 Kiel, Germany

[3] Hannover Med Sch, Dept Pediat Hematol & Oncol, D-3000 Hannover, Germany

来源：

LEUKEMIA | 2006年 / 20卷 / 02期

关键词：

D O I：

10.1038/sj.leu.2404060

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：381 / 383

页数：4

共 8 条

[1] JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia
Jelinek, J
Oki, Y
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Issa, JPJ
[J]. BLOOD, 2005, 106 (10) : 3370 - 3373
[2] Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
Jones, AV
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Zoi, K
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Curtis, C
Zhang, LY
Score, J
Seear, R
Chase, AJ
Grand, FH
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Zoi, C
Loukopoulos, D
Terpos, E
Vervessou, EC
Schultheis, B
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Cross, NCP
[J]. BLOOD, 2005, 106 (06) : 2162 - 2168
[3] A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
Lacronique, V
Boureux, A
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Quang, CT
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Berthou, C
Lessard, M
Berger, R
Ghysdael, J
Bernard, OA
[J]. SCIENCE, 1997, 278 (5341) : 1309 - 1312
[4] The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia
Levine, RL
Loriaux, M
Huntly, BJP
Loh, ML
Beran, M
Stoffregen, E
Berger, R
Clark, JJ
Willis, SG
Nguyen, KT
Flores, NJ
Estey, E
Gattermann, N
Armstrong, S
Look, AT
Griffin, JD
Bernard, OA
Heinrich, MC
Gilliland, DG
Druker, B
Deininger, MWN
[J]. BLOOD, 2005, 106 (10) : 3377 - 3379
[5] The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2
Reiter, A
Walz, C
Watmore, A
Schoch, C
Blau, I
Schlegelberger, B
Berger, U
Telford, N
Aruliah, S
Yin, JA
Vanstraelen, D
Barker, HF
Taylor, PC
O'Driscoll, A
Benedetti, F
Rudolph, C
Kolb, HJ
Hochhaus, A
Hehlmann, R
Chase, A
Cross, NCP
[J]. CANCER RESEARCH, 2005, 65 (07) : 2662 - 2667
[6] JAKing up hematopoietic proliferation
Shannon, K
Van Etten, RA
[J]. CANCER CELL, 2005, 7 (04) : 291 - 293
[7] The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes
Steensma, DP
Dewald, GW
Lasho, TL
Powell, HL
McClure, RF
Levine, RL
Gilliland, DG
Tefferi, A
[J]. BLOOD, 2005, 106 (04) : 1207 - 1209
[8] The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia
Sulong, S
Case, M
Minto, L
Wilkins, B
Hall, A
Irving, J
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2005, 130 (06) : 964 - 965

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