Extremely high enantioselective redox reaction of ketones and alcohols catalyzed by RuCl2(PPh3)(oxazolinylferrocenylphosphine)

被引：161

作者：

Nishibayashi, Y

Takei, I

Uemura, S ^{[1
]}

Hidai, M

机构：

[1] Univ Tokyo, Dept Chem & Biotechnol, Grad Sch Engn, Tokyo 1138656, Japan

[2] Kyoto Univ, Grad Sch Engn, Dept Energy & Hydrocarbon Chem, Sakyo Ku, Kyoto 6068501, Japan

来源：

ORGANOMETALLICS | 1999年 / 18卷 / 12期

关键词：

D O I：

10.1021/om990210o

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The ruthenium complex RuCl2(PPh3)(oxazolinylferrocenylphosphine), 1, has been found to be a quite effective catalyst for asymmetric transfer hydrogenation of not only alkyl aryl ketones but also alkyl methyl ketones with (PrOH)-Pr-i. Asymmetric oxidation of racemic sec-alcohols with acetone via kinetic resolution by using the same catalyst 1 also proceeds with exteremely high enantioselectivity (>99.9% ee).

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页码：2291 / 2293

页数：3

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