Phage variation: understanding the behaviour of an accidental pathogen

被引：17

作者：

Moxon, ER ^{[1
]}

Jansen, VAA

机构：

[1] Weatherall Inst Mol Med, Mol Infect Dis Grp, Oxford OX3 9DU, England

[2] Univ Oxford, Dept Paediat, John Radcliffe Hosp, Oxford OX3 9DU, England

[3] Univ London Royal Holloway & Bedford New Coll, Sch Biol Sci, Egham TW20 0EX, Surrey, England

来源：

TRENDS IN MICROBIOLOGY | 2005年 / 13卷 / 12期

关键词：

D O I：

10.1016/j.tim.2005.10.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Understanding why carriers of meningococci occasionally develop invasive disease is a major challenge. Individual strains of meningococci are extremely variable and undergo dynamic changes in DNA content and organization. This heterogeneity of meningococcal populations might enhance the fitness of this human-restricted bacterium. The recent discovery of a meningococcal bacteriophage and its associations to disease is an intriguing example of this variability and could contribute to a better understanding of microbial commensal and virulence behaviour.

引用

页码：563 / 565

页数：3

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