Synthesis of chiral difluorinated [6]-gingerol

被引:15
作者
Fukuda, H [1 ]
Tetsu, M [1 ]
Kitazume, T [1 ]
机构
[1] TOKYO INST TECHNOL,DEPT BIOENGN,MIDORI KU,YOKOHAMA,KANAGAWA 226,JAPAN
关键词
D O I
10.1016/0040-4020(95)00868-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Total synthesis of chiral difluorinated [6]-gingerol using key intermediates (R)-(+)- and (S)-(-)-ethyl 2,2-difluoro-3-hydroxyoctanoates, obtained via enzymatic resolution with olipase/4S (Rhizopus japonicus) is described.
引用
收藏
页码:157 / 164
页数:8
相关论文
共 30 条