Experimental assessment of PowerFeed chromatography

被引：32

作者：

Zhang, ZY

Morbidelli, M ^{[1
]}

Mazzotti, M

机构：

[1] ETH, Inst Chem & Bioengn, Swiss Fed Inst Technol, CH-8093 Zurich, Switzerland

[2] ETH, Inst Proc Engn, CH-8092 Zurich, Switzerland

来源：

AICHE JOURNAL | 2004年 / 50卷 / 03期

关键词：

PowerFeed process; simulated moving bed; experiment; multiobjective optimization; process design; chiral separation;

D O I：

10.1002/aic.10056

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

The PowerFeed process is a modification of the simulated moving bed (SMB) technique, where the flow rates in the unit are allowed to change during a switching period following a predefined pattern. Through multiobjective optimization, using a genetic algorithm, it is shown that PowerFeed achieves better performances than SMB in several cases of interest for applications. Moreover, its experimental feasibility and effectiveness is assessed by running and comparing SMB and PowerFeed separations of the enantiomers of alpha-ionone, on a cyclodextrin based chiral stationary phase. (C) 2004 American Institute of Chemical Engineers.

引用

页码：625 / 632

页数：8

共 30 条

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