Development of a concise and diversity-oriented approach for the synthesis of plecomacrolides via the diene-ene RCM

被引：40

作者：

Lu, K ^{[1
]}

Huang, MW ^{[1
]}

Xiang, Z ^{[1
]}

Liu, YX ^{[1
]}

Chen, JH ^{[1
]}

Yang, Z ^{[1
]}

机构：

[1] Peking Univ, Key Lab Bioorgan Chem & Mol Engn,Lab Chem Genet, Minist Educ,Sch Pharmaceut Sci,Shenzhen Grad Sch, Coll Chem,State Key Lab Nat & Biomimet Drugs, Beijing 100871, Peoples R China

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 06期

关键词：

D O I：

10.1021/ol060221v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise synthesis of the core structures of plecomacrolide with ring sizes varying from 16 to 19 atoms was achieved for the first time by the diene-ene ring-closing olefin metathesis reaction. This approach should allow access to the structurally diverse analogues of plecomacrolide.

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收藏

页码：1193 / 1196

页数：4

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