Submicromolar, selective G-quadruplex ligands from one pot:: Thermodynamic and structural studies of human telomeric DNA binding by azacyanines

被引：18

作者：

Cetinkol, Oezguel Persil ^{[1
]}

Engelhart, Aaron E. ^{[1
]}

Nanjunda, Rupesh K. ^{[2
,3
]}

Wilson, W. David ^{[2
,3
]}

Hud, Nicholas V. ^{[1
]}

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Parker H Petit Inst Bioengn & Biosci, Atlanta, GA 30332 USA

[2] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA

[3] Georgia State Univ, Ctr Biotechnol & Drug Design, Atlanta, GA 30303 USA

来源：

CHEMBIOCHEM | 2008年 / 9卷 / 12期

基金：

美国国家科学基金会;

关键词：

cancer; DNA structures; drug design; quadruplexes; telomeres;

D O I：

10.1002/cbic.200800234

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1889 / 1892

页数：4

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