A G-quadruplex ligand with 10000-fold selectivity over duplex DNA

被引：170

作者：

Dixon, Isabelle M.

Lopez, Frederic

Tejera, Agueda M.

Esteve, Jean-Pierre

Blasco, Maria A.

Pratviel, Genevieve

Meunier, Bernard

机构：

[1] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France

[2] Hop Rangueil, Inst Louis Bugnard, IFR 31, INSERM, F-31059 Toulouse, France

[3] Spanish Natl Canc Ctr, Madrid 28029, Spain

[4] Inst Louis Bugnard, INSERM, U 531, Hop Rangueil, F-31059 Toulouse 9, France

[5] Palumed, F-31682 Labege, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 06期

关键词：

D O I：

10.1021/ja065591t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A cationic manganese porphyrin binds strongly and selectively to G-quadruplex DNA. This compound is the most selective G4- igand reported to date.

引用

页码：1502 / +

页数：3

共 30 条

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